唾液乳桿菌(Lactobacillus salivarius)
簡介
唾液乳桿菌(Lactobacillus salivarius)屬于乳桿菌科(Lactobacillaceae),革蘭陽性、無芽孢桿菌,兼性厭氧。 現名稱:唾液共生乳桿菌(Ligilactobacillus salivarius)。
臨床相關性
益生菌,用于某些疾病的輔助治療。偶見合并其它菌引起食管吻合口膿腫(Peripharyngeal esophageal anastomotic abscess)、糖尿病酮癥酸中毒病人菌血癥、膿胸、膽囊炎、減肥術并發腹腔感染等。天然對萬古霉素耐藥。
藥敏試驗
微量肉湯稀釋法(裂解馬血陽離子調節肉湯)檢測MIC,受試抗生素及其折點參考M45ED3 Table11;對來自無菌部位標本(如血液、深部組織)的分離株,特別是免疫缺陷患者的菌株需要進行藥敏試驗;青霉素、氨芐西林、達托霉素、利奈唑胺罕見“非敏感”表型。該菌種對萬古霉素天然耐藥;嚴重的感染例如心內膜炎治療時常使用青霉素及慶大霉素聯用。
參考文獻
1.Itoh N,et al.A mixed infection involving Bacteroides denticanum, Lactobacillus salivarius, and Streptococcus anginosus as causative agents of abscess around a
pharyngo-esophageal anastomosis and acute vertebral osteomyelitis:Identification by ribosomal RNA sequencing of bacterial isolates.JInfect Chemother.2023 Aug;29(8):816-819.
2.Wang HK,et al. Lactobacillus salivarius empyema with respiratory failure.JMicrobiol Immunol Infect.2017 Dec;50(6):923-925.
3.Woo PC,et al.Identification by 16S rRNA gene sequencing of Lactobacillus salivarius bacteremic cholecystitis.JClin Microbiol.2002Jan;40(1):265-7.
4.Garcia Carretero R,et al.Lactobacillus salivariusinfection as a postoperative complication after bariatric surgery.Enferm Infecc Microbiol Clin(Engl Ed).2018 Jan;36(1):60-61.


